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Local dynamics in biological macromolecules
Author(s) -
Perico Angelo
Publication year - 1989
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360280905
Subject(s) - macromolecule , chemistry , statistical physics , relaxation (psychology) , hierarchy , simple (philosophy) , chemical physics , chain (unit) , molecular dynamics , nanosecond , biological system , computational chemistry , physics , quantum mechanics , psychology , social psychology , biochemistry , philosophy , epistemology , economics , market economy , biology , laser
The diffusive approach in the optimized Rouse–Zimm approximation to segment relaxation in the nanosecond time domain (ORZLD) is extended to consider chains of nonequivalent units as occurring in biological macromolecules. The correlation times for second‐order time correlation functions of each virtual bond on the chain are calculated for some homopolypeptides, and random and regular copolypeptides. The expected correlation times for biological macromolecules organized in multiple domains are discussed via a simple model of the ORZLD hierarchy. Dynamic bond correlation times are compared with static local presistence lengths.