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On the stretching of DNA in the reptation theories of gel electrophoresis
Author(s) -
Slater Gary W.,
Rousseau Jean,
Noolandi Jaan
Publication year - 1987
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360260607
Subject(s) - reptation , chemistry , electrophoresis , gel electrophoresis , dna , field (mathematics) , gel electrophoresis of nucleic acids , chromatography , polymer , biochemistry , organic chemistry , mathematics , pure mathematics
The reptation dynamics of DNA chains in gel electrophoresis is discussed. The differences between the Lumpkin, Déjardin, and Zimm (LDZ), and the Slater and Noolandi (SN), biased reptation models are pointed out and studied. We show that new assumptions are necessary in order to study large‐field electrophoresis, and we present preliminary results of a computer simulation of DNA gel electrophoresis.