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Pf1 virus particle dynamics
Author(s) -
Tsang P.,
Opella S. J.
Publication year - 1986
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360251004
Subject(s) - chemistry , protein filament , particle (ecology) , dynamics (music) , anisotropy , virus , chemical physics , crystallography , biophysics , virology , physics , biochemistry , optics , oceanography , acoustics , biology , geology
Abstract The overall dynamics of the Pf1 filamentous bacteriophage particle in solution are characterized by nmr experiments. The chemical‐shift anisotropy powder‐pattern lineshapes from both DNA and protein backbone sites of the virus are motionally averaged in the same way, indicating that the entire particle undergoes rapid (< 10 4 Hz) reorientation about the long axis of the filament when the virus is in solution at high pH. In contrast, the virus particles in samples at low pH are immobile on this time scale.