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Analysis of the interaction of membrane‐active peptides with membranes: The case of melittin in surfactant assemblies
Author(s) -
Chandani Bina,
Balasubramanian D.
Publication year - 1986
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360250707
Subject(s) - melittin , chemistry , membrane , biophysics , pulmonary surfactant , polarity (international relations) , peptide , biochemistry , cell , biology
Some of the factors that govern the interaction between membrane‐active peptides and membranes were analyzed using melittin as an example. The structural properties of melittin were studied in a variety of micellar and reverse micellar assemblies of varying sizes, shapes, and net charges. The roles of the polarity, packing, and the charge carried by the host assembly on the structural features of the incorporated melittin are delineated. Such an analysis is expected to be of relevance to other membrane‐active peptides as well.