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Crowned dopa's, their dimers, cyclodimers and polymers: Synthesis and cation complexation
Author(s) -
Berthet Michele,
Sonveaux Etienne
Publication year - 1986
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360250113
Subject(s) - chemistry , alanine , dipeptide , protonation , crown ether , tetrahydrofuran , cooperativity , glycine , polymer chemistry , ammonium , monomer , potassium , stereochemistry , medicinal chemistry , polymer , amino acid , organic chemistry , ion , solvent , biochemistry
Optically pure protected L ‐[3,4‐(1,4,7,10,13‐pentaoxatridecamethylene) phenyl] alanine, its dipeptide, diketopiperazine and homopolymer, protected L ‐[3,4‐(1,4,7,10,13,16‐hexaoxahexadecamethylene) phenyl] alanine and its polymer have been synthesized and characterized. These crown ether derivatives complex the potassium and ammonium cations as well as protonated leucine and glycine in tetrahydrofuran and methanol. They are also phase‐transfer agents. The cooperativity of the crown units was studied in detail for the dimeric ligands.