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Properties of the aminotyrosine derivatives of calmodulin
Author(s) -
Steiner R. F.,
Marshall L.
Publication year - 1985
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360240309
Subject(s) - chemistry , calmodulin , tyrosine , matrix (chemical analysis) , biophysics , biochemistry , chromatography , biology , enzyme
Derivatives of calmodulin have been prepared in which tyrosine‐99 and tyrosine‐138 have been converted to their aminotyrosine derivatives. Significant changes in microenvironment occur in the presence of Ca 2+ . Both groups have a significant degree of mobility with respect to the protein matrix; this is Ca 2+ dependent.