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Mathematical models of depolymerization of amylose by α‐amylases
Author(s) -
Mazur A. K.
Publication year - 1984
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360230909
Subject(s) - depolymerization , amylose , chemistry , interpretation (philosophy) , stability (learning theory) , amylase , biological system , computational chemistry , enzyme , organic chemistry , starch , computer science , machine learning , biology , programming language
For a long time the action pattern of depolymerizing enzymes was explored by examining the distribution of products. Some attempts to interpret the data on the action of α‐amylases on amylose quantitatively have led to conflicting results. In the present work, new mathematical models are developed based on the properties of the most‐probable distribution and on the recently established fact of its partial stability at enzyme depolymerization. Published data for several α‐amylases are reexamined in light of this theoretical analysis. The theory proposed permits us to resolve a controversy concerning the interpretation of experimental data in this field.