Premium
Structure of amphotericin B aggregates based on calculations of optical spectra
Author(s) -
Hemenger R. P.,
Kaplan Theodore,
Gray L. J.
Publication year - 1983
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360220312
Subject(s) - chemistry , aqueous solution , degenerate energy levels , amphotericin b , spectral line , polymer , optical spectra , molecule , absorption spectroscopy , ground state , absorption (acoustics) , computational chemistry , crystallography , chemical physics , organic chemistry , optics , atomic physics , physics , quantum mechanics , antifungal , medicine , dermatology
The Degenerate ground state approximation was used to calculate the optical absorption and CD spectra for helical polymer models of amphotericin B aggregates in aqueous solution. Comparisons with experimental spectra indicate that a two‐molecule/unit cell helical polymer model is a possible structure for aggregates of amphotericin B.