Premium
Vibrational analysis of conformation in peptides, polypeptides, and proteins
Author(s) -
Krimm S.
Publication year - 1983
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360220130
Subject(s) - bacteriorhodopsin , chemistry , molecule , polypeptide chain , glycine , helix (gastropod) , crystallography , amino acid , biochemistry , membrane , organic chemistry , snail , biology , ecology
A vibrational force field for the polypeptide chain has been developed for normal‐mode analysis of such molecules. It can reproduce observed frequencies of known structures to within about 5 cm −1 . We review the application of this technique to conformational problems in peptides (β‐turns and their model compounds), polypeptides [the α II ‐helix and crystalline poly(glycine II)], and proteins (bacteriorhodopsin and glucagon).
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom