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Anomalous temperature dependence of frictional coefficients: Diffusion and sedimentation measurement of low‐density lipoproteins, albumin, and polystyrene latex
Author(s) -
Crossley J. M.,
Spraggs S. P.,
Creeth J. M.,
Noble N.,
Slack J.
Publication year - 1982
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360210118
Subject(s) - chemistry , diffusion , polystyrene , atmospheric temperature range , analytical chemistry (journal) , solvent , sedimentation , thermodynamics , chromatography , polymer , organic chemistry , paleontology , physics , sediment , biology
Using quasielastic light scattering, we have determined the diffusion coefficients of low‐density lipoprotein (LDL) and polystyrene latex spheres over the temperature range of 293–318 K. The results show that after correction for thermal changes in the solvent, there remains a residual negative temperature coefficient in the diffusion amounting to about −0.6%/K that is independent of the chemical type of complex. Confirmation of these results was obtained for LDL through sedimentation studies over a similar range of temperatures. The residual temperature coefficient was similar to that reported for oxyhemoglobin [W. B. Veldkamp and R. Votano (1980) Biopolymers 19 , 111–124] and greater than that found for bovine serum albumin by these and earlier workers. These observations show that the residual dependence on temperature is not an isolated phenomenon and could in part be explained by increased aggregation of particles, although this is not the primary cause of the effect.