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Size and shape determination of apotransferrin and transferrin monomers
Author(s) -
Rosseneumotreff M. Y.,
Soetewey F.,
Lamote R.,
Peeters H.
Publication year - 1971
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360100610
Subject(s) - transferrin , chemistry , monomer , molecule , dispersion (optics) , ellipsoid , aqueous solution , viscosity , crystallography , biochemistry , polymer , thermodynamics , organic chemistry , physics , astronomy , optics
Dielectric dispersion and viscosity measurement, s were performed on apotransferrin and transferrin monomers in aqueous solutions so as to check the influence of iron binding on the overall conformation of the molecule. Iron saturation by two iron atoms per transferrin molecule modifies the parameters of the equivalent ellipsoid. The molecule becomes more spherical while its hydration value remains high.