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Tautomerism in cytidine
Author(s) -
Johnson W. C.,
Vipond P. M.,
Girod J. C.
Publication year - 1971
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360100514
Subject(s) - cytidine , tautomer , chemistry , solvent , aqueous solution , absorption spectroscopy , solvent effects , photochemistry , broad spectrum , computational chemistry , combinatorial chemistry , organic chemistry , quantum mechanics , physics , enzyme
The large change in the electronic absorption spectrum of cytidine on going from an aqueous to an aprotic medium is attributed to the existence of a hydrogen bonded solvent‐solute complex in solvents capable of donating a proton. The spectrum of cytidine in a variety of solvents and the spectra of a number of nontautomerising model compounds are presented. The tautomerisin of cytidine and its biological implications are discussed.