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Determination of the dominant factors which influence the net hydration of native sodium deoxyribonucleate
Author(s) -
Hearst John E.
Publication year - 1965
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.360030107
Subject(s) - solvation , chemistry , dilution , mole fraction , electrolyte , solvent , salt (chemistry) , thermodynamics , mole , activity coefficient , sodium , solvation shell , inorganic chemistry , aqueous solution , organic chemistry , physics , electrode
A theory for the dependence of the net thermodynamic solvation of a macroion in an electrolyte solution is presented. The solvation in moles salt/mole macroion is shown to approach – | Z p |/ v in the limit of infinite dilution of salt and macroion. The solvation in moles water/mole macroion is shown to approach zero at zero water activity. Isopiestic determinations of the hydration of sodium deoxyribonucleate in NaCl, Na 2 SO 4 , and NaClO 4 solutions indicate that short‐range interactions of the NaDNA with solvent account for more than half of the observed solvation. The net hydration appears to be predominantly influenced only by water activity.