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Publication year - 2020
Publication title -
biopolymers
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.23303
Subject(s) - chemistry , protonation , peptoid , fragmentation (computing) , ion , residue (chemistry) , dissociation (chemistry) , collision induced dissociation , tandem mass spectrometry , stereochemistry , mass spectrometry , crystallography , peptide , chromatography , organic chemistry , biochemistry , computer science , operating system
Peptoids belong to a class of sequence‐controlled polymers containing N ‐alkylglycine units. Ren et al. use tandem mass spectrometry to characterize the fragmentation patterns of some singly and doubly protonated peptoids with one basic residue at different positions. Upon collision‐induced dissociation, a charged peptoid dissociates into two sets of charged fragments: B‐ions, containing the N‐terminal residue (structure on the left); and Y‐ions, containing the C‐terminal residue (structure on the right). The Y‐ions are of higher abundance than the B‐ions, revealing that the C‐terminal fragments have a higher affinity toward the charge carrier, the proton. (DOI: 10.1002/bip.23358 )