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Single molecule studies of molecular diffusion in cellular membranes: Determining membrane structure
Author(s) -
Ritchie Ken,
Spector Jeff
Publication year - 2007
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.20801
Subject(s) - membrane , chemistry , molecule , biophysics , cell membrane , diffusion , membrane structure , cell , biochemistry , biology , organic chemistry , physics , thermodynamics
Abstract Since the advent of single particle/molecule microscopies, researchers have applied these techniques to understanding the fluid membranes of cells. By observing diffusion of membrane proteins and lipids in live cell membranes of eukaryotic cells, it has been found that membranes contain a mosaic of fluid compartments. Such structure may be instrumental in understanding key characteristics of the membrane. Recent single molecule observations on prokaryotic cell membranes will also be discussed. © 2007 Wiley Periodicals, Inc. Biopolymers 87: 95–101, 2007. This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com