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Effect of diethylsulfoxide on the thermal denaturation of DNA
Author(s) -
Markarian Shiraz A.,
Asatryan Arpine M.,
Grigoryan Karine R.,
Sargsyan Hasmik R.
Publication year - 2006
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.20454
Subject(s) - preprint , chemistry , dna , aqueous solution , denaturation (fissile materials) , thermal , polymer science , nanotechnology , organic chemistry , thermodynamics , nuclear chemistry , biochemistry , physics , materials science , computer science , world wide web
Abstract DNA thermal denaturation has been investigated in aqueous solutions of diethylsulfoxide (DESO) by means of UV‐vis and densimetry methods. It is suggested that, on the one hand, the structural change of entire solutions and, on the other hand, a direct interaction of DESO with DNA are responsible for the observed peculiar behavior. The results obtained were compared with those of dimethylsulfoxide (DMSO), also known from literature © 2006 Wiley Periodicals, Inc. Biopolymers 82: 1–5, 2006 This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com