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Sodium chloride enhanced oligomerization of L ‐arginine
Author(s) -
Xin Liang,
Ma YanLin,
Liu YiNan,
Yan Qin,
Wang KongJiang
Publication year - 2006
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.20354
Subject(s) - chemistry , arginine , yield (engineering) , aqueous solution , sodium , homogeneous , chloride , guanidinium chloride , biophysics , medicinal chemistry , inorganic chemistry , biochemistry , amino acid , organic chemistry , enzyme , materials science , physics , biology , metallurgy , thermodynamics
NaCl significantly enhanced the longer oligoarginine formation in the oligomerization of L ‐arginine activated by N,N ′‐carbonyldiimidazole (CDI) in homogeneous aqueous solution. The optimal concentration of NaCl for the highest yield of longer oligoarginine formation is around 1 M . It is suggested that the weak interactions of Cl − with the positive‐charged guanidinium group of the oligoarginines formed in the oligomerization of L ‐arginine are responsible for the enhancement by NaCl. © 2005 Wiley Periodicals, Inc. Biopolymers 81: 1–7, 2006 This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com