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Quality control of Harpagophytum procumbens and its related phytopharmaceutical products by means of NIR‐FT‐Raman spectroscopy
Author(s) -
Baranska M.,
Schulz H.,
Siuda R.,
Strehle M. A.,
Rösch P.,
Popp J.,
Joubert E.,
Manley M.
Publication year - 2005
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.20158
Subject(s) - chemistry , raman spectroscopy , quality (philosophy) , optics , physics , quantum mechanics
NIR‐FT‐Raman spectroscopy was used for identification and quantification of harpagoside in secondary roots of Harpagophytum procumbens as well as in related phytopharmaceutical products, e.g., ethanolic extracts and tablets. Applied Raman mappings reveal the spatial distribution of this valuable iridoid glycoside within the different samples. The same technique can be used for quality control purposes beginning from the plant to its final products. Based on the obtained spectral data and reference HPLC values of harpagoside, a reliable multivariate calibration model was developed. © 2004 Wiley Periodicals, Inc. Biopolymers, 2005