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Poly(ε‐ L ‐lysine): Synthesis and conformation
Author(s) -
Kushwaha D. R. S.,
Mathur K. B.,
Balasubramanian D.
Publication year - 1980
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.1980.360190202
Subject(s) - lysine , antiparallel (mathematics) , chemistry , stereochemistry , side chain , amino acid , derivative (finance) , polypeptide chain , biochemistry , polymer , organic chemistry , physics , quantum mechanics , magnetic field , financial economics , economics
The synthesis of poly(ε‐ L ‐lysine) is described. This is a poly(ε‐amino acid) in which the ε‐amino group of lysine is condensed with the α‐carboxyl group to produce a chain backbone that is a variant of the usual one seen in proteins and the side chain is the α‐amino group. Conformational studies of poly(ε‐ L ‐lysine) and its t ‐butyloxycarbonyl derivative suggest the likelihood of a chain order that is formally similar to the antiparallel pleated‐sheet conformation of proteins.