Premium
The effect of polydispersity on the nuclear magnetic resonancxce spectra of ply‐ Y ‐benzyl‐ L ‐glutamate
Author(s) -
Milstien Julie B.,
Ferretti James A.
Publication year - 1973
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.1973.360121012
Subject(s) - dispersity , chemistry , nucleation , gel permeation chromatography , spectral line , random coil , nmr spectra database , helix (gastropod) , nuclear magnetic resonance , crystallography , polymer chemistry , organic chemistry , circular dichroism , polymer , ecology , physics , astronomy , snail , biology
The effect of poly dispersity on the nuclear magnetic resonance spectra of samples of poly‐γ‐benzyl‐ L ‐glutamateein the helix–random coil transition is studied. In the transitionregion the α‐CH proton resonance shows two peaks whose behavior does not change appreciably upon fractionation by gel permeation chromatography. Theoretical spectra were computed with both a polydispersity model of the transition and a model for slow nucleationof helix from completely random coil molecules. The results suggest that the double peak behavior in the nmr spectra results from a slow rate of helix nucleation rather than polydispersity.