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The effect of temperature on acid condensation of DNA
Author(s) -
Dore E.,
Frontali C.,
Gratton E.
Publication year - 1973
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.1973.360120519
Subject(s) - chemistry , condensation , dna , dna condensation , molecule , chemical physics , biophysics , thermodynamics , organic chemistry , biochemistry , transfection , physics , gene , biology
The temperature dependence of the condensation phenomenon observed for DNA at low pH is studied in 1 M NaCl. The similarity of the effects of an increase in temperature and of a decrease in pH gives some insight into the physical nature of the interactions hindering the unwinding of the DNA molecule in the condensed state.