Premium
Theory of chromatography of macromolecules with rigid structures on hydroxyapatite columns. I. Static part
Author(s) -
Kawasaki Tsutomu
Publication year - 1970
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.1970.360090305
Subject(s) - chemistry , macromolecule , adsorption , molecule , diffusion , chromatography , phase (matter) , solvent , function (biology) , macro , thermodynamics , chemical engineering , organic chemistry , biochemistry , physics , evolutionary biology , biology , computer science , programming language , engineering
A theory for the chromatography of rigid macromolecules on hydroxyapatite columns has been developed under the assumptions of instantaneous thermodynamic equilibrium between adsorbed phase and solution and of negligible longitudinal diffusion of macro‐molecules. In the first or static part of this theory the adsorption isotherm of macro‐molecules was studied as a function of phosphate concentration in the solvent.