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Stereochemistry of nucleic acids and polynucleotides. V. Conformational energy of a ribose‐phosphale unit
Author(s) -
Lakshminarayanan A. V.,
Sasisekharan V.
Publication year - 1969
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.1969.360080406
Subject(s) - polynucleotide , nucleic acid , chemistry , ribose , sugar , monomer , sugar phosphates , crystallography , stereochemistry , unit (ring theory) , phosphate , biochemistry , polymer , organic chemistry , mathematics education , mathematics , enzyme
The potential energy calculations on the sugar‐phosphate unit for different puckerings of the sugar are reported in this paper. The results obtained here essentially confirm our earlier predictions made by using criteria of contact distances (hard‐sphere potential) and are also supported by observed conformation in crystal structures. The minimum energy conformations of the sugar phosphate unit, along with the preferred orientations of the base with respect to the sugar given in the previous paper, determine the probable conformations of the monomer unit of a polynucleotide (or nucleic acid) chain.