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Conformational aspects of polypeptides. XXIX. Conformationl assignments for some aromatic polypeptides by far‐uv cotton effects. New results
Author(s) -
Goodman Murray,
Toniolo Claudio,
Peggion Evaristo
Publication year - 1968
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.1968.360061203
Subject(s) - optical rotatory dispersion , chemistry , chromophore , circular dichroism , cotton effect , amide , peptide , wavelength , crystallography , stereochemistry , photochemistry , organic chemistry , biochemistry , optics , physics
Recent improvements in apparatus permit the examination of circular dichroism (CD) and optical rotatory dispersion (ORD) spectra to 185 mμ. In addition, new solvents which are transparent to 185 mμ have become available for synthetic polypeptides. The spectral region 185–250 mμ is extremely important for the amide (peptide) chromophore, because of the presence at these wavelengths of the n –π* and π–π* bands, 1 and of another transition, the assignment of which remains unsettled. 2