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Ionic polysaccharides. II. Comparison of polyelectrolyte behavior of hyaluronatc with that of carboxymethyl cellulose
Author(s) -
Cleland Robert L.
Publication year - 1968
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.1968.360061102
Subject(s) - carboxymethyl cellulose , chemistry , polyelectrolyte , virial coefficient , electrolyte , polymer , polymer chemistry , sodium , ionic bonding , cellulose , isoelectric point , ionic strength , intrinsic viscosity , thermodynamics , aqueous solution , chromatography , organic chemistry , ion , physics , electrode , enzyme
Sodium hyaluronate (NaHy) and sodium carboxymethyl cellulose (NaCMC) behave similarly with respect to concentration. N 3 of an added 1 : 1 electrolyte. The second virial coefficient A 2 (light scattering) is identical within experimental error at a given. N 3 . The limiting viscosity number [η] also varies with N 3 −1/2 in similar fashion for samples of similar [η] of the two polymers. Differences in Na + activity in salt‐free solutions are interpreted on the basis of weaker Na + binding in NaHy, presumably due to the greater charge separation along its chain backbone. Added electrolyte is excluded in dialysis more strongly by NaHy (or its acid form) than by NaCMC. The Flory parameter Φ is smaller in good solvents for NaHy, as for many other polyelectrolytes, than for nonionic polymers.