Premium
X‐Ray diffraction studies of the conformation of macromolecules in solution. III. The helix–coil transition
Author(s) -
Brady George W.,
Salovey R.
Publication year - 1967
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.1967.360050402
Subject(s) - trifluoroacetic acid , chemistry , macromolecule , diffraction , helix (gastropod) , dimethylformamide , electromagnetic coil , random coil , crystallography , rotation (mathematics) , x ray , organic chemistry , optics , physics , circular dichroism , solvent , biology , biochemistry , geometry , mathematics , quantum mechanics , snail , ecology
The procedure outlined in the previous paper of this series is applied to x‐ray diffraction patterns of labeled polytyrosine in dimethylformamide–trifluoroacetic acid solutions. The α‐helix appears to transform into the random coil conformation at a trifluoroacetic acid concentration between 40 and 42.5%. Comparison of these results with those measured in the same system by optical rotation are in essential agreement.