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X‐ray diffraction studies of the conformation of polymer molecules in solution. II. Poly‐3,5‐dibromotyrosine
Author(s) -
Brady George W.,
Salovey R.,
Reddy J. M.
Publication year - 1965
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/bip.1965.360030508
Subject(s) - chemistry , diffraction , polymer , intensity (physics) , molecule , dimethylformamide , bromine , helix (gastropod) , scattering , crystallography , solvent , oscillation (cell signaling) , optics , physics , organic chemistry , ecology , biochemistry , snail , biology
X‐ray diffraction patterns from dilute solutions of poly‐3,5‐dibromo‐ L ‐tyrosine in dimethylformamide and equivalent concentrations of 2,6‐dibromophenol in the same solvent are compared. The intensity difference as a function of scattering angle is indicative of the arrangement of residues in the polymer. A novel averaging procedure is used to compute the intensity patterns arising from regular arrays of bromine atoms. Interbromine spacings measured on a Drieding model of a right‐handed α‐helix with side groups restricted to rigid positions of maximum stagger give moderate agreement with experiment. Very good agreement with observations is obtained by allowing for a small oscillation of phenyl rings which effectively cancels out the contribution of large distances to the intensity curve.