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Mass Balance Model with Donnan Equilibrium Accurately Describes Unusual pH and Excipient Profiles during Diafiltration of Monoclonal Antibodies
Author(s) -
Baek Youngbin,
Singh Nripen,
Arunkumar Abhiram,
Borwankar Ameya,
Zydney Andrew L.
Publication year - 2020
Publication title -
biotechnology journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.144
H-Index - 84
eISSN - 1860-7314
pISSN - 1860-6768
DOI - 10.1002/biot.202070093
Subject(s) - diafiltration , excipient , monoclonal antibody , mathematical proof , chemistry , balance (ability) , chromatography , antibody , mathematics , membrane , biochemistry , biology , immunology , neuroscience , microfiltration , geometry