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Dielectrophoretic Manipulation of Janus Particle in Conductive Media for Biomedical Applications
Author(s) -
Lee Minji,
Won Jong Bin,
Jung Dae Ho,
Kim Jaekyoung,
Choi Yonghyun,
Akyildiz Kubra,
Choi Jonghoon,
Kim Kyobum,
Cho Jiung,
Yoon Hyunsik,
Koo HyungJun
Publication year - 2020
Publication title -
biotechnology journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.144
H-Index - 84
eISSN - 1860-7314
pISSN - 1860-6768
DOI - 10.1002/biot.202000343
Subject(s) - janus , dielectrophoresis , janus particles , materials science , particle (ecology) , nanotechnology , homogeneous , electrohydrodynamics , conductivity , electrical conductor , electric field , chemistry , physics , composite material , microfluidics , oceanography , quantum mechanics , geology , thermodynamics
Janus particles are applied to many fields including biomedical applications. To expand the usability of Janus particles, a technique to manipulate the particle movement is required. A dielectrophoresis (DEP) method can be a promising candidate; however, independent manipulation or separation of Janus particle by DEP is still challenging. Additionally, DEP of Janus particles in conductive media is important especially for biomedical applications where ion‐rich media are typically used. Here, the experimental results of DEP‐induced transport and separation of the Janus particle in conductive media are presented. To predict the DEP behavior, the Clausius–Mossotti (CM) factors of both Janus and homogeneous particles are calculated, depending on the alternating current (AC) frequency and medium conductivity. The Janus particles show the positive‐DEP behavior at the entire AC frequency region tested due to the metal‐coated half surface. On the other hand, the homogeneous particles show the negative‐DEP behavior at the high AC frequency or in conductive media. Additionally, in the conductive media, an electrohydrodynamic flow hinders the DEP‐driven particle transport below MHz AC frequencies. Finally, the separation of the Janus particles from the homogeneous ones is experimentally demonstrated and the separation efficiency is discussed based on the evaluation parameters established in this study.