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An Overview on the Toxicological Properties of Ionic Liquids toward Microorganisms
Author(s) -
Sivapragasam Magaret,
Moniruzzaman Muhammad,
Goto Masahiro
Publication year - 2020
Publication title -
biotechnology journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.144
H-Index - 84
eISSN - 1860-7314
pISSN - 1860-6768
DOI - 10.1002/biot.201900073
Subject(s) - biochemical engineering , biocompatible material , ionic liquid , bioaccumulation , nanotechnology , chemistry , pharmaceutics , environmental chemistry , microbiology and biotechnology , materials science , organic chemistry , biology , engineering , pharmacology , biomedical engineering , catalysis
Abstract Ionic liquids (ILs), a class of materials with unique physicochemical properties, have been used extensively in the fields of chemical engineering, biotechnology, material sciences, pharmaceutics, and many others. Because ILs are very polar by nature, they can migrate into the environment with the possibility of inclusion in the food chain and bioaccumulation in living organisms. However, the chemical natures of ILs are not quintessentially biocompatible. Therefore, the practical uses of ILs must be preceded by suitable toxicological assessments. Among different methods, the use of microorganisms to evaluate IL toxicity provides many advantages including short generation time, rapid growth, and environmental and industrial relevance. This article reviews the recent research progress on the toxicological properties of ILs toward microorganisms and highlights the computational prediction of various toxicity models.