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Inside Back Cover: Biotechnology Journal 5/2018
Publication year - 2018
Publication title -
biotechnology journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.144
H-Index - 84
eISSN - 1860-7314
pISSN - 1860-6768
DOI - 10.1002/biot.201870053
Subject(s) - citation , synthetic biology , cover (algebra) , computer science , computational biology , microbiology and biotechnology , biology , world wide web , engineering , mechanical engineering
Reducing leaky gene expression is critical for improving protein yield of recombinant bacteria and stability of engineered cellular circuits in synthetic biology. The image illustrates a repurposed, modular CRISPRi system that attenuates leaky gene expression from a promoter. The corresponding publication establishes a new application of CRISPRi in genomic engineering to improve the control of recombinant gene expression. Image credit: Lia Wesp. This is reported by Sean R. McCutcheon, Kwan Lun Chiu, Daniel D. Lewis, and Cheemeng Tan, article number 1700167 .