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Metabolic Engineering for Advanced Biofuels Production and Recent Advances Toward Commercialization
Author(s) -
Meadows Corey W.,
Kang Aram,
Lee Taek S.
Publication year - 2018
Publication title -
biotechnology journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.144
H-Index - 84
eISSN - 1860-7314
pISSN - 1860-6768
DOI - 10.1002/biot.201600433
Subject(s) - commercialization , biofuel , renewable energy , biochemical engineering , renewable fuels , metabolic engineering , microbiology and biotechnology , production (economics) , biorefinery , business , renewable resource , natural resource economics , environmental science , engineering , economics , biology , marketing , ecology , biochemistry , macroeconomics , enzyme
Research on renewable biofuels produced by microorganisms has enjoyed considerable advances in academic and industrial settings. As the renewable ethanol market approaches maturity, the demand is rising for the commercialization of more energy‐dense fuel targets. Many strategies implemented in recent years have considerably increased the diversity and number of fuel targets that can be produced by microorganisms. Moreover, strain optimization for some of these fuel targets has ultimately led to their production at industrial scale. In this review, the recent metabolic engineering approaches for augmenting biofuel production derived from alcohols, isoprenoids, and fatty acids in several microorganisms are discussed. In addition, the successful commercialization ventures for each class of biofuel targets are discussed.