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Supercapacitive transport of pharmacologic agents using nanoporous gold electrodes
Author(s) -
Gittard Shaun D.,
Pierson Bonnie E.,
Ha Cindy M.,
Wu ChungAn Max,
Narayan Roger J.,
Robinson David B.
Publication year - 2010
Publication title -
biotechnology journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.144
H-Index - 84
eISSN - 1860-7314
pISSN - 1860-6768
DOI - 10.1002/biot.200900250
Subject(s) - chronoamperometry , nanoporous , materials science , supercapacitor , cyclic voltammetry , electrode , electrochemistry , nanotechnology , chemical engineering , pseudocapacitor , chemistry , engineering
In this study, nanoporous gold supercapacitors were produced by electrochemical dealloying of gold‐silver alloy. Scanning electron microscopy and energy dispersive X‐ray spectroscopy confirmed completion of the dealloying process and generation of a porous gold material with ∼10 nm diameter pores. Cyclic voltammetry and chronoamperometry of the nanoporous gold electrodes indicated that these materials exhibited supercapacitor behavior. The storage capacity of the electrodes measured by chronoamperometry was ∼3 mC at 200 mV. Electrochemical storage and voltage‐controlled delivery of two model pharmacologic agents, benzylammonium and salicylic acid, was demonstrated. These results suggest that capacitance‐based storage and delivery of pharmacologic agents may serve as an alternative to conventional drug delivery methods.