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Airborne particle monitoring in clean room environments for stem cell cultures
Author(s) -
Cobo Fernando,
Grela David,
Conchal Aacute;ngel
Publication year - 2008
Publication title -
biotechnology journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.144
H-Index - 84
eISSN - 1860-7314
pISSN - 1860-6768
DOI - 10.1002/biot.200700122
Subject(s) - particle (ecology) , stem cell , environmental science , nanotechnology , materials science , biology , microbiology and biotechnology , ecology
Abstract Modern high‐technology industrial practices like pharmaceutical and stem cell line production demand high‐quality environmental conditions to avoid particle contamination in the final product. Particles are important because their presence can affect both the output and the productivity and because they can have repercussion on human health. In this kind of production practice it is necessary to implement optimal methods for particle management and to introduce an environmental monitoring program. This should also address the regional regulatory requirements and will depend on local conditions in each processing center. Each center must evaluate its specific needs and establish appropriate monitoring procedures.