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Novel biocatalysts for white biotechnology
Author(s) -
Drepper Thomas,
Eggert Thorsten,
Hummel Werner,
Leggewie Christian,
Pohl Martina,
Rosenau Frank,
Wilhelm Susanne,
Jaeger KarlErich
Publication year - 2006
Publication title -
biotechnology journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.144
H-Index - 84
eISSN - 1860-7314
pISSN - 1860-6768
DOI - 10.1002/biot.200600059
Subject(s) - biochemical engineering , microbiology and biotechnology , enantiopure drug , isolation (microbiology) , industrial biotechnology , directed evolution , computational biology , enzyme , biology , biochemistry , gene , engineering , catalysis , enantioselective synthesis , mutant
White Biotechnology uses microorganisms and enzymes to manufacture a large variety of chemical products. Therefore, the demand for new and useful biocatalysts is steadily and rapidly increasing. We have developed methods for the isolation of new enzyme genes, constructed novel expression systems, and optimized existing enzymes for biotechnological applications by methods of directed evolution. Furthermore, we have isolated and characterized biocatalysts relevant for the preparation of enantiopure compounds.