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The effect of dietary and plasma fatty acids on platelet aggregation in senior generation of Japanese women
Author(s) -
Takachi Ribeka,
Kimira Mitsuru,
Uesugi Sayo,
Kudo Yoko,
Ouchi Kazuyuki,
Watanabe Shaw
Publication year - 2004
Publication title -
biofactors
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.204
H-Index - 94
eISSN - 1872-8081
pISSN - 0951-6433
DOI - 10.1002/biof.5520220143
Subject(s) - platelet aggregation , fatty acid , platelet , long chain , food science , chemistry , medicine , endocrinology , biochemistry , polymer science
Dietary factors that influence platelet aggregation have not been fully clarified in humans. 63 Japanese women, aged 40–70 years old, completed one‐day weighted dietary records, and received physical and laboratory examinations. Platelet aggregation was measured by 1.0 and 3.0 μM ADP induction. The results were analyzed with special reference to fatty acids. The short and medium chain fatty acid intake showed negative correlation with maximum percent of platelet aggregation induced by 1.0 μM ADP. Short and medium chain fatty acids in this study were mostly derived from milk and dairy products. Importance of short and medium chain fatty acid intake on platelet aggregation requires further study for prevention of cardiovascular diseases.