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CoQ 10 : Could it have a role in cancer management?
Author(s) -
Hodges S.,
Hertz N.,
Lockwood K.,
Lister R.
Publication year - 1999
Publication title -
biofactors
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.204
H-Index - 94
eISSN - 1872-8081
pISSN - 0951-6433
DOI - 10.1002/biof.5520090237
Subject(s) - cancer , coenzyme q – cytochrome c reductase , coenzyme q10 , clinical trial , medicine , immune system , oncology , bioinformatics , biology , immunology , biochemistry , apoptosis , cytochrome c
Coenzyme Q 10 or ubiquinone has been shown to have both anti‐cancer and immune system enhancing properties when tested in animals. Preliminary results reported here suggest that it might inhibit tumour‐associated cytokines. Clinical studies conducted with combination therapies of CoQ 10 and other antioxidants are ongoing, but the results are difficult evaluate owing to the lack of proper control groups and of initial randomisation. Also on the basis of some anti‐cancer effects of antioxidants reported in literature, further animal studies and a proper clinical trial of coenzyme Q 10 in cancer patients are needed.