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Recent advances in fluorescence sensors based on DNA–MOF hybrids
Author(s) -
Wu Fen,
Ye Jianhan,
Cao Yulu,
Wang Ziyuan,
Miao Tingting,
Shi Qian
Publication year - 2020
Publication title -
luminescence
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 45
eISSN - 1522-7243
pISSN - 1522-7235
DOI - 10.1002/bio.3790
Subject(s) - dna , fluorescence , nucleic acid , chemistry , nanotechnology , peptide nucleic acid , metal ions in aqueous solution , computational biology , combinatorial chemistry , biophysics , biochemistry , ion , materials science , biology , organic chemistry , physics , quantum mechanics
In this review, the recent advances in the development of fluorescence sensors based on DNA and metal–organic framework hybrids have been reported for nucleic acid, metal ion and amino acid detection. The main detection mechanism depends on different adsorption capacities of MOFs towards different DNA structures (single‐stranded DNA, double‐stranded DNA), and consequently the fluorescence intensity of probe DNA is changed. These results might open up a way to study their potential application in material science and clinical diagnosis of some related diseases.