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A near‐infrared fluorescent probe based on boric acid hydrolysis for hydrogen peroxide detection and imaging in HeLa cells
Author(s) -
Wang Tao,
Yang Xiaojun,
Men Jinxia,
Zhou Jinpei,
Zhang Huibin
Publication year - 2020
Publication title -
luminescence
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 45
eISSN - 1522-7243
pISSN - 1522-7235
DOI - 10.1002/bio.3715
Subject(s) - hydrogen peroxide , boric acid , fluorescence , hela , chemistry , photochemistry , cleave , hydrolysis , peroxide , biochemistry , organic chemistry , enzyme , in vitro , optics , physics
Summary Using the characteristics of hydrogen peroxide that are able to cleave phenyl‐boric acid selectively and efficiently, we here report a dicyanoisophorone‐boric acid ( DCP‐BA )‐based near‐infrared (NIR) fluorescent probe for detection of hydrogen peroxide. This probe shows a rapid, highly selective, and sensitive detection process for hydrogen peroxide with a significant NIR fluorescent turn‐on response that has been successfully applied to detect exogenous hydrogen peroxide in HeLa cells.