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A simple gold nanoplasmonic SERS method for trace Hg 2+ based on aptamer‐regulating graphene oxide catalysis
Author(s) -
Li Chongning,
Wang Xiaoliang,
Liang Aihui,
Luo Yanghe,
Wen Guiqing,
Jiang Zhiliang
Publication year - 2018
Publication title -
luminescence
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 45
eISSN - 1522-7243
pISSN - 1522-7235
DOI - 10.1002/bio.3517
Subject(s) - graphene , trisodium citrate , aptamer , catalysis , colloidal gold , oxide , detection limit , raman scattering , chemistry , raman spectroscopy , nanotechnology , nanomaterials , linear range , nanoparticle , inorganic chemistry , photochemistry , materials science , nuclear chemistry , chromatography , organic chemistry , optics , physics , biology , genetics
The as‐prepared graphene oxide (GO) exhibited a strong catalytic effect on reduction of HAuCl 4 by trisodium citrate to form gold nanoplasmons (AuNPs) with a strong surface‐enhanced Raman scattering (SERS) effect at 1615 cm −1 in the presence of molecular probe Victoria blue 4R (VB4r). SERS intensity increased with nanocatalyst GO concentration due to the formation of more AuNP substrates. The aptamer (Apt) of Hg 2+ can bind to GO to form Apt–GO complexes, which can strongly inhibit nanocatalysis. When target Hg 2+ is present, the formed stable Hg 2+ –Apt complexes are separated from the GO surface, which leads to GO catalysis recovery. The enhanced SERS signal was linear to Hg 2+ concentration in the range 0.25–10 nmol/L, with a detection limit of 0.08 nmol/L Hg 2+ . Thus, a new gold nanoplasmon molecular spectral analysis platform was established for detecting Hg 2+ , based on Apt regulation of GO nanocatalysis.