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Highly selective and sensitive coumarin–triazole‐based fluorometric ‘turn‐off’ sensor for detection of Pb 2+ ions
Author(s) -
Kumar Ajay,
Parveen Iram,
Ahmed Naseem
Publication year - 2018
Publication title -
luminescence
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 45
eISSN - 1522-7243
pISSN - 1522-7235
DOI - 10.1002/bio.3468
Subject(s) - detection limit , naked eye , fluorescence , chemistry , ion , stoichiometry , selectivity , photochemistry , chromatography , organic chemistry , physics , quantum mechanics , catalysis
Exposure to even very low concentrations of Pb 2+ is known to cause cardiovascular, neurological, developmental, and reproductive disorders, and affects children in particular more severely. Consequently, much effort has been dedicated to the development of colorimetric and fluorescent sensors that can selectively detect Pb 2+ ions. Here, we describe the development of a triazole‐based fluorescent sensor L5 for Pb 2+ ion detection. The fluorescence intensity of chemosensor L5 was selectively quenched by Pb 2+ ions and a clear color change from colorless to yellow could be observed by the naked eye. Chemosensor L5 exhibited high sensitivity and selectivity towards Pb 2+ ions in phosphate‐buffered solution [20 mM, 1:9 DMSO/H 2 O (v/v), pH 8.0] with a 1:1 binding stoichiometry, a detection limit of 1.9 nM and a 6.76 × 10 6 M −1 binding constant. Additionally, low‐cost and easy‐to‐prepare test strips impregnated with chemosensor L5 were also produced for efficient of Pb 2+ detection and proved the practical use of this test.