Premium
Highly luminescent nitrogen‐doped carbon dots for simultaneous determination of chlortetracycline and sulfasalazine
Author(s) -
Zhang Zhengwei,
Chen Jianqiu,
Duan Yu,
Liu Weixia,
Li Dan,
Yan Zhengyu,
Yang Ke
Publication year - 2018
Publication title -
luminescence
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 45
eISSN - 1522-7243
pISSN - 1522-7235
DOI - 10.1002/bio.3416
Subject(s) - detection limit , fluorescence , quantum yield , linear range , nanosensor , chemistry , carbon fibers , quenching (fluorescence) , hydrothermal carbonization , sulfamerazine , analytical chemistry (journal) , nuclear chemistry , materials science , nanotechnology , chromatography , carbonization , organic chemistry , physics , quantum mechanics , adsorption , composite number , composite material , sulfadiazine , biochemistry , antibiotics
Here, we have presented a green and facile strategy to fabricate nitrogen‐doped carbon dots (N‐CDs) and their applications for determination of chlortetracycline (CTC) and sulfasalazine (SSZ). The fluorescent N‐CDs, prepared by one‐step hydrothermal reaction of citric acid and l ‐arginine, manifested numerous excellent features containing strong blue fluorescence, good water‐solubility, narrow size distribution, and a high fluorescence quantum yield (QY) of 38.8%. Based on the fluorescence quenching effects, the as‐synthesized N‐CDs as a fluorescent nanosensor exhibited superior analytical performances for quantifying CTC and SSZ. The linear range for CTC was calculated to be from 0.85 to 20.38 μg ml −1 with a low detection limit of 0.078 μg ml −1 . Meanwhile, the linear range for SSZ was estimated to be from 0.34 to 6.76 μg ml −1 with a low detection limit of 0.032 μg ml −1 . Therefore, the N‐CDs hold admirable application potential for constructing a fluorescent sensor for pharmaceutical analysis.