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One‐step synthesis of nitrogen, boron co‐doped fluorescent carbon nanoparticles for glucose detection
Author(s) -
Liang Meijuan,
Ren Yi,
Zhang Haijuan,
Ma Yunxia,
Niu Xiaoying,
Chen Xingguo
Publication year - 2017
Publication title -
luminescence
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 45
eISSN - 1522-7243
pISSN - 1522-7235
DOI - 10.1002/bio.3287
Subject(s) - boronic acid , fluorescence , detection limit , heteroatom , boron , carbon fibers , quenching (fluorescence) , nanoparticle , chemistry , inorganic chemistry , combinatorial chemistry , materials science , nanotechnology , chromatography , organic chemistry , ring (chemistry) , physics , quantum mechanics , composite material , composite number
Heteroatom‐doped carbon nanoparticles (CNPs) have attracted considerable attention due to an effective improvement in their intrinsic properties. Here, a facile and simple synthesis of nitrogen, boron co‐doped carbon nanoparticles (NB‐CNPs) from a sole precursor, 3‐aminophenylboronic acid, was performed via a one‐step solid‐phase approach. Because of the presence of boronic acid, NB‐CNPs can be used directly as a fluorescent probe for glucose. Based on a boronic acid‐triggered specific reaction, we developed a simple NB‐CNP probe without surface modification for the detection of glucose. When glucose was introduced, the fluorescence of NB‐CNPs was suppressed through a surface‐quenching states mechanism. Obvious fluorescence quenching allowed the highly sensitive determination of glucose with a limit of detection of 1.8 μM. Moreover, the proposed method has been successfully used to detect glucose in urine from people with diabetes, suggesting potential application in sensing glucose.