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Investigation on 1 O 2 generation ability of di‐sulfonic phthalocyanine zinc isomers using an HPLC–CL system
Author(s) -
Jiang Zhou,
Chen Meili,
Hu Yanli,
Wang Jian,
Chen Guonan
Publication year - 2013
Publication title -
luminescence
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 45
eISSN - 1522-7243
pISSN - 1522-7235
DOI - 10.1002/bio.2460
Subject(s) - chemiluminescence , chemistry , singlet oxygen , high performance liquid chromatography , zinc , phthalocyanine , photochemistry , chromatography , medicinal chemistry , oxygen , organic chemistry
ABSTRACT An HPLC system combining a chemiluminescence detector was applied to estimate the singlet oxygen ( 1 O 2 ) generation ability of di‐sulfonic phthalocyanine zinc (ZnPcS 2 ) isomers. As photosensitizers, ZnPcS 2 produces 1 O 2 in air‐saturated solutions under photoirradiation. The latter reacts with methyl Cypridina luciferin analogue (MCLA) to initiate chemiluminescence. This photoinduced chemiluminescence (PCL) of MCLA provides an easy method for evaluating the isomers' 1 O 2 generation ability during a simultaneous HPLC separation procedure. The cis ‐isomers and trans ‐isomers of ZnPcS 2 show different 1 O 2 generation abilities, which are in accordance with differences in their absorption spectra. Copyright © 2013 John Wiley & Sons, Ltd.