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Scavenging capacities of some thiazolyl thiazolidine‐2,4‐dione compounds on superoxide radical, hydroxyl radical, and DPPH radical
Author(s) -
Kruk Irena,
BozdağDündar Oya,
CeylanÜnlüsoy Meltem,
Ertan Rahmiye,
AboulEnein Hassan Y.,
Michalska Teresa
Publication year - 2009
Publication title -
luminescence
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 45
eISSN - 1522-7243
pISSN - 1522-7235
DOI - 10.1002/bio.1105
Subject(s) - dpph , chemistry , scavenging , radical , hydroxyl radical , superoxide , chemiluminescence , thiazolidine , electron paramagnetic resonance , antioxidant , medicinal chemistry , photochemistry , organic chemistry , physics , nuclear magnetic resonance , enzyme
The scavenging effects of eighteen thiazolyl thiazolidine‐2,4‐dione compounds (TTCs) on superoxide radical – •2 , hydroxyl radical HO • , and 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH • ) radical were evaluated by the chemiluminescence technique, electron spin resonance spectrometry (ESR) and visible spectrophotometry, respectively. The examined compounds were shown to have 27–59% – •2scavenging ability, 19–69% HO • scavenging activity and 2–32% DPPH • scavenging ability. This property of the tested compound seems to be important in the prevention of various diseases of free radicals etiology. Copyright © 2009 John Wiley & Sons, Ltd.