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Highly sensitive spectrofluorimetric determination of trace amounts of prulifloxacin using the aluminium(III)–prulifloxacin system
Author(s) -
Yu Fengshan,
Liu Weizhou,
Chen Fang,
Cai Ping
Publication year - 2008
Publication title -
luminescence
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.428
H-Index - 45
eISSN - 1522-7243
pISSN - 1522-7235
DOI - 10.1002/bio.1075
Subject(s) - chromatography , chemistry , detection limit , fluorescence , dodecylbenzene , analytical chemistry (journal) , sulfonate , sodium , organic chemistry , physics , quantum mechanics
The fluorescence of the prulifloxacin (PUFX)–Al(III) system was investigated . Experiments indicated that the fluorescence intensity of prulifloxacin could be greatly enhanced by Al(III) and sensitized by sodium dodecylbenzene sulphonate (SDBS). Accordingly, a sensitive spectrofluorimetric method for the determination of prulifloxacin was established. While excited at 275 nm, the enhanced fluorescence intensity at 412 nm of the system (Δ F ) showed a good linear relationship with the concentration of prulifloxacin within the range 4.0 × 10 –8 –3.0 × 10 –6 mol/L. The regression equation was Δ F = 9.83 + 10.8 × 10 7 c (mol/L); the correlation coefficient and detection limit (3 σ /k) were 0.99901 and 2.0 × 10 –8 mol/L, respectively. The proposed method has been successfully applied to determine prulifloxacin in real pharmaceutical samples. The luminescence mechanism of the system is also discussed in detail. Copyright © 2008 John Wiley & Sons, Ltd.