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On Robust Linear Regression of Hepatic Extraction of Insulin
Author(s) -
Aboukalam M. A. F.
Publication year - 1997
Publication title -
biometrical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.108
H-Index - 63
eISSN - 1521-4036
pISSN - 0323-3847
DOI - 10.1002/bimj.4710390205
Subject(s) - linear regression , regression , insulin , extraction (chemistry) , regression analysis , statistics , mathematics , computer science , medicine , chromatography , chemistry
In classical linear regression model for analysis of medical data concerning hepatic extraction of insulin and c‐peptide the fundamental assumption is that the subjects involved are of a similar nature. In reality, if this assumption is violated then the precision of the results is questionable. This paper suggests a robust alternative to overcome this problem. It is observed that the robustification may be a better option to determine an optimal quantity of insulin which minimizes the risk of damage associated with diabatic treatments.