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Multieentre Clinical Trials and Variance Components
Author(s) -
McGilchrist C. A.,
Zhaorong J.
Publication year - 1990
Publication title -
biometrical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.108
H-Index - 63
eISSN - 1521-4036
pISSN - 0323-3847
DOI - 10.1002/bimj.4710320505
Subject(s) - statistics , negative binomial distribution , binomial regression , binomial distribution , mathematics , regression analysis , econometrics , variance (accounting) , count data , clinical trial , medicine , accounting , business , poisson distribution
A method of analysing regression data is presented for a model in which the dependent variable has a binomial distribution and the regression contains both fixed and random components. The method is then used to analyse treatment success data for a multicentre clinical trial study.
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