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Log‐Linear Model Analysis of the Disease‐Genotype Association Problem: Two‐Loci Case
Author(s) -
Khamis H. J.
Publication year - 1986
Publication title -
biometrical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.108
H-Index - 63
eISSN - 1521-4036
pISSN - 0323-3847
DOI - 10.1002/bimj.4710280206
Subject(s) - log linear model , association (psychology) , genotype , genetic association , statistics , linear model , mathematics , genetics , biology , psychology , gene , single nucleotide polymorphism , psychotherapist
The log‐linear model is modified in order to adapt it to the disease‐genotype association problem, where two loci are involved. By so doing, the structure of associations among the genetic variables can be determined, and sources of distortion can be identified in certain test statistics and coefficients of association.