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A New Estimation Method for Noncompartmental Pharmacokinetic Analysis
Author(s) -
Knolle H.
Publication year - 1986
Publication title -
biometrical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.108
H-Index - 63
eISSN - 1521-4036
pISSN - 0323-3847
DOI - 10.1002/bimj.4710280107
Subject(s) - estimation , pharmacokinetics , mathematics , computer science , econometrics , statistics , medicine , pharmacology , economics , management
The mathematical tools of Hilbert space theory and Gauß quadrature are used to derive a new method of curve fitting and calculation of statistical moments of the concentration‐time curve.